QT interval – Its measurement and clinical significance
نویسندگان
چکیده
منابع مشابه
Measurement of the QT interval.
Ventricular repolarization is reflected by the T-wave of the surface electrocardiogram, the QT interval being the time taken for ventricular recovery. QT measurement has assumed clinical importance as prolongation is associated with a variety of conditions includingthe Romano-Ward' and JervellLange-Neilson syndromes, drug toxirity' and an adverse prognosis following acute myocardial infarction....
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The QT interval, apart from clinical implications is crucial for safety assessment of new drugs under development. A QTc prolongation of even 10 msec in a study group is a warning signal for a new drug. There are various issues involved in the measurement of the QT interval especially regarding the ending of the T wave and different morphological pattern of T-U complex. The other issue is signi...
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There has been an increasing focus on drug induced QT prolongation including research on drug development and QT prolongation, following the removal of drugs due to torsades de pointes (TdP). Although this has improved our understanding of drug-induced QT prolongation there has been much less research aimed at helping clinicians assess risk in individual patients with drug induced QT prolongati...
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The long QT syndrome is an arrhythmogenic channelopathy characterized by severe alterations in ventricular repolarization, electrocardiographically translated as a QT interval prolongation. The involvement of various ion channels in the genesis of cardiac action potential causes that alterations in their structure and function lead to the so-called syndrome and to the presence of malignant vent...
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Aprolonged QT interval signifies a delay in the ventricular repolarisation phase, which renders the heart vulnerable to malignant arrhythmias such as torsade de pointes ventricular tachycardia. This sign of disease is sometimes subtle and may avoid recognition unless meticulously sought. In this issue of Heart, Malik and colleagues draw attention to methodological difficulties in the measuremen...
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ژورنال
عنوان ژورنال: Journal of Clinical and Preventive Cardiology
سال: 2019
ISSN: 2250-3528
DOI: 10.4103/jcpc.jcpc_44_18